Know Your Lung Cancer Risk
Before It’s Too Late: A Case Study

Lung cancer remains the leading cause of cancer-related deaths worldwide—and it’s often detected too late. At TrueYouOmics, we’re changing that.

By combining deep proteomics with lifestyle data, we’ve built a model that predicts lung cancer risk with surprising accuracy—giving individuals and healthcare providers the insights they need to act early.

Why Early Detection Matters

Every year, over 10 million people die from cancer—and nearly half of those deaths could be avoided with better prevention and early diagnosis.

Lung cancer, in particular, is deadly because it’s usually caught at a late stage. That’s where our work comes in.

What We Did: Risk Stratification Through Proteomics

Using a dataset of over 50,000 individuals from the UK Biobank, we developed a machine learning model that classifies people into low, medium, and high-risk categories for lung cancer.

Low-risk group

0.01%

General 5-year risk

0.38%

High-risk group

1.03%

The percentages you see—0.01% (green), 0.38% (white), and 1.03% (red)—represent real-world 5-year incidence rates of lung cancer observed in our study cohort.

The white box (0.38%) shows the actual incidence in the general population, regardless of risk level.
The green box (0.01%) represents individuals our model predicted as low-risk—and they truly had an extremely low rate of developing lung cancer.

The red box (1.03%) reflects those predicted as high-risk by our model—and they were far more likely to develop the disease.

Survival Matters: What the Data Shows

Our Kaplan-Meier survival analysis reveals what this means over time:

• People in the low-risk group show almost perfect survival probability over 5 years.

• Those in the high-risk group see a noticeable decline.

Can You Trust the Model?
Yes. Here’s Why.

We validated our model rigorously.

• Time-dependent AUC stays consistently high over 5 years

• Concordance index across folds ~0.88

These are strong indicators that our model performs well—not just in theory, but in practice.

Why Knowing Your Risk Matters

Why Knowing Your Risk Matters

If you’re at high risk and don’t know it, chances are you’ll only be diagnosed once symptoms appear—and by then, treatment options are limited.


Knowing your risk early gives you the power to take action:

• Stop smoking (or avoid passive smoke)

• Measure radon in your home—6.7% of US homes have elevated levels

• Avoid exposure to asbestos

• Eat more fruits and vegetables (+20% risk reduction)

• Stay physically active (+20% risk reduction)

Small changes. Big difference.

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Location

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TrueYouOmics © 2024. All rights reserved.
TrueYouOmics is currently in the stage of validating product-market fit and, as such, does not have any products available for purchase at this time. The information provided in this landing page is for informational purposes only and does not constitute an offer or solicitation to buy any products or services. Please note that the details shared on this landing page are subject to change as we continue to develop and refine our product offering. Please read our privacy-policy to understand how we treat your data and your rights.

Location

Neuchâtel, Switzerland

TrueYouOmics © 2024. All rights reserved.
TrueYouOmics is currently in the stage of validating product-market fit and, as such, does not have any products available for purchase at this time. The information provided in this landing page is for informational purposes only and does not constitute an offer or solicitation to buy any products or services. Please note that the details shared on this landing page are subject to change as we continue to develop and refine our product offering. Please read our privacy-policy to understand how we treat your data and your rights.